Paracetamol (Acetaminophen) Decreases Hydrogen Sulfide Tissue Concentration in Brain but Increases It in the Heart, Liver and Kidney in Mice
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Paracetamol (acetaminophen) decreases hydrogen sulfide tissue concentration in brain but increases it in the heart, liver and kidney in mice.
The biological action ofN-acetyl-p-aminophenol - paracetamol (acetaminophen) has been demonstrated to involve different mechanisms and is still not clear. Hydrogen sulfide (H2S) has been shown to play an important role in many physiological and pathological processes including nociception. The interaction between acetaminophen and endogenous H2S is unknown. Twenty four female CBA strain mice we...
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ژورنال
عنوان ژورنال: Folia Biologica
سال: 2011
ISSN: 0015-5497
DOI: 10.3409/fb59_1-2.41-44